This is a list of the largest U.S. cities that do not currently have teams in the following professional leagues: the NFL, the NBA, the NHL, Major League Baseball, or Major League Soccer. Out of the largest 50 cities, 11 currently do not have franchises in the "major" major leagues.
Large cities that are part of a "Metroplex" such as Fort Worth, Mesa, or Long Beach are considered to be represented by the metro-area team (Dallas, Phoenix, LA, etc). For this list, if a team is named for an entire state (Arizona Diamondbacks or Texas Rangers) it is not considered a city's team if located more than 100 miles away (or if the city is not located in the same state.) So, for the purposes of this list, the Texas Rangers aren't the city team for El Paso or Austin, but the Colorado Rockies are for Colorado Springs since Denver is only 60 miles away.
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Albuquerque
2013 est. population: 556,495
Austin
2013 estimated population: 885,400
Strong NCAA following for UT Longhorns
Other area teams include:
Austin Outlaws (Women's Football Alliance)
Austin Toros (NBA Development League)
Texas Stars (American Hockey League)
Austin Aztex (USL Premier Development League)
El Paso
2013 estimated population: 674,433
Home of the Sun Bowl
Area professional teams include:
El Paso Chihuahuas (AAA Baseball - Pacific Coast League)
El Paso Patriots (Soccer - future league o be determined)
El Paso Rhinos (Western States Hockey League)
Fresno
2013 est. population: 509,924
Las Vegas
2013 est. population: 603.488
Louisville
2013 Est. Population: 609,893
Strong support for NCAA team: Louisville Cardinals
Area Professional Teams include:
Louisville Bats (AAA Baseball - International League)
Louisville Lightning (Indoor Soccer)
Kentucky Stickhorses (North American Lacrosse League)
Kentucky Xtreme (Indoor Football)
Louisville City (USL Pro Soccer)
Omaha
2013 est. population: 434,353
Tucson
2013 est. population: 526,116
Tulsa
2013 est. population: 398,121
Virginia Beach
2013 est. population: 448,479
Virginia is the most populous state without a professional sports team as of 2014. The Virginia Beach-Norfolk Metro region is the second largest after Austin-Round Rock to lack a major league team.